Vijaychem Industries

ISO 9001:2008 Certified Company

Zinc Sulphate - Heptahydrate :
Chemical Stability & Toxicological Information

CHEMICAL STABILITY:
Conditions Contributing To Instability
Presence of incompatible materials.
Product is considered stable.
Hazardous polymerisation will not occur.
NOTE: Fat incompatible materials - refer to page - Handling and Storage.
TOXICOLOGICAL INFORMATION :
Potential Health Effects
Acute Health Effects: Swallowed
Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual.
Sulfates are not well absorbed orally, but can cause diarrhoea.
Soluble zinc salts produce irritation and corrosion of the alimentary tract with pain, and vomiting. Death can occur due to insufficiency of food intake due to severe narrowing of the oesophagus and pylorus.
Eye :
If applied to the eyes, this material causes severe eye damage.
Skin :
There is some evidence to suggest that this material can cause inflammation of the skin on contact in some persons.
Solution of material in moisture on the Skin, or perspiration, may increase irritant effects.
Open cuts, abraded or irritated skin should not be exposed to this material.
Entry into the blood-stream, through, for example. Cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.
Inhaled :
There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage.
Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.
If prior damage to the circulatory or nervous systems has occurred or if kidney damage has been sustained. proper screenings should be conducted on individuals who may be exposed to further risk if handling and use of the material result In excessive exposures
Limited evidence exists that this substance may cause irreversible mutations (though not lethal) even following a single exposure.
Chronic Health Effects :
There is some evidence from animal testing that exposure to this material may result in toxic effects to the unborn baby. Based on laboratory and animal testing, exposure to the material may result in irreversible effects and mutations in humans.
Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis; caused by particles less than 0.5 micron penetrating and remaining in the lung. Prime symptom is breathlessness; lung shadows show on X-ray.
Welding or name cutting of metals with zinc or zinc dust coatings may result in inhalation of zinc oxide fume; high concentrations of zinc oxide fume may result in "metal fume fever"; also known as "brass chills", an industrial disease of short duration, [I.L.O] Symptoms Include malaise, fever, weakness, nausea and may appear quickly if operations occur in enclosed or poorly ventilated areas.
Toxicity & Irritation :
Unless otherwise specified data extracted from RTECS- Register of Toxic Effects of Chemical Substances.
Common Name Irritation
Oral (human) TDLo: 45 mg/kg/7d-C Eye (rabbit): 0.,42 mg Moderate
Oral (human) TDLo: 106 mg/kg Nil Reported
Oral (man) TDLo: 180 mg/kg/6w-I  
Oral (rat) LD50: 2949 mg/kg  
Unreported (man) LDLo: 221 mg/kg  
Oral (rat) L050: 1260 mg/kg  
Intraperitoneal (rat) LD50: 200 mg/kg  
Oral (mouse) LD50: 200 mg/kg  
Intraperitoneal (mouse) LD50: 75 mg/kg  
Limited Evidence Of A Carcinogenic Effect
Equivocal tumorigenic agent by RTECS criteria for zinc sulfate heptahydrate :
Sleep, ataxia, respiratory stimulation. somnolence, coma, diarrhoea, changes in endocrine pancreas recorded.
NOTE: Substance has been shown to be mutagenic in at least one assay, or belongs to a family of chemicals producing damage or Change to cellular DNA.